Speaker: NICOLE GERVAIS, Psychology, University of Toronto
Title: Role of ovarian hormones in memory and sleep across species
Ebbinghaus Empire Series 2018-2019
Video Recording of Talk
Abstract: Sex hormones impact all body systems including the central nervous system, where they act both directly and indirectly to influence behaviour and brain function. Seminal work has shown that these hormones affect the organization of the brain during prenatal development. Following puberty, these same hormones exert activational effects that influence several behaviours andcognitive abilities across species. In females, these effects are pronounced during periods of hormonal fluctuation including puberty, pregnancy, and the menopausal transition. I will discuss findings in both humans and animal models of menopause demonstrating how ovarian hormone deprivation impacts memory. I will also discuss the role ovarian hormones play in promoting sleep, which may itself promote memory. I conclude by discussing ways to address the gap in the literature with respect to how ovarian hormones impact sleep and memory during development, as well as normal and pathological aging.
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