Speaker: RANDY McINTOSH, Rotman Research Institute
Title: Bridging data and theory with The Virtual Brain
Ebbinghaus Empire Series 2018-2019
Video Recording of Talk
Abstract: The Virtual Brain (TVB) is a generative modelling platform to combine empirical data with dynamic models and produce large-scale simulations of brain networks. In the presentation, I will first cover the TVB architecture and summarize the current applications. I will then cover two research streams: The first using biophysical models to better understand the interaction of local and distributed operations in constraining cognitive function. The second uses a phenomenological model to predict the propagation of epileptic seizures, emphasizing the interplay of fast and slow dynamics around seizure onset. I hope to convince you that TVB, and more generally computational modelling, can be valuable for merging data and theory to better understand brain function and dysfunction.
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