W. Dale Stevens, Department of Psychology, York University
Title: What Can Resting-State Functional Connectivity MRI Reveal About Higher-Level Cognition?
Ebbinghaus Empire Series 2014-2015
VIDEO RECORDING OF TALK
Abstract: Analysis of spontaneously correlated low-frequency activity fluctuations across the brain using functional MRI - commonly referred to as resting-state functional connectivity (RSFC) MRI - was initially seen as a useful tool for mapping functional-anatomic networks in the living human brain, characterizing brain changes and differences in clinical populations, and studying comparative anatomy across species. However, little was known about the potential relevance of RSFC to cognitive processes. Indeed, there has been considerable controversy and debate as to the utility of studying the resting-state in cognitive neuroscience. However, recent work has shown that RSFC, rather than merely reflecting passive or epiphenomenal activity within underlying brain networks, reveals important dynamic processes that play an active role in cognition. In this talk, I will present my recent work demonstrating that RSFC is functionally relevant to human behavior and higher-level cognition - including perception, language, learning and memory, and the organization of conceptual knowledge - and propose a hypothesis regarding its mechanism of action on functional network dynamics and cognition.
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